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Image Search Results
Journal: Scientific Reports
Article Title: Differential regulation of TRP channel gene and protein expression by intervertebral disc degeneration and back pain
doi: 10.1038/s41598-019-55212-9
Figure Lengend Snippet: TaqMan primers used for the qPCR analysis.
Article Snippet: PKD1 , Polycystin 1, Transient Receptor Potential Channel Interacting ,
Techniques:
Journal: Archives of Toxicology
Article Title: Chlordecone: development of a physiologically based pharmacokinetic tool to support human health risks assessments
doi: 10.1007/s00204-022-03231-3
Figure Lengend Snippet: Conceptual representation of the PBPK model to study CD exposure in rats and humans. For rats, only CD is described, as there is almost none of the metabolite CD-OH. For humans, CD-OH is present as the major metabolite. The structure is the same for both species
Article Snippet: These figures appear to be lower than the CD TLV external (0.17 μg/kg bw/day) recommended by the ANSES using the
Techniques:
Journal: Archives of Toxicology
Article Title: Chlordecone: development of a physiologically based pharmacokinetic tool to support human health risks assessments
doi: 10.1007/s00204-022-03231-3
Figure Lengend Snippet: A Distribution of CD following a single intravenous exposure to 1 mg CD/kg bw. The experimental data were from Bungay et al. . B Distribution of CD following exposure to 0.33 mg of CD/kg bw in the diet for three days. The experimental data were from Richter et al. . C Distribution of CD following oral exposure to 5 ppm in the diet for 90 days and sampling 24 h after the last exposure on day 91 (2184 h the beginning of the treatment). The experimental data were from Linder et al. . D Distribution of CD in male rats after a single oral dose of 40 mg/kg bw. The experimental data were from Belfiore et al. . _Sim is the simulation profile and _Exp is the experimental data measured. The CD concentration (mg/L) or (µg/L) is shown on the Y axes and the hours or days on the X axes. Cb CD in the blood, Cbr CD in the brain, CF CD in the adipose tissue, CLi CD in the liver
Article Snippet: These figures appear to be lower than the CD TLV external (0.17 μg/kg bw/day) recommended by the ANSES using the
Techniques: Sampling, Concentration Assay